What Episode Does Orochimaru Die

Okay, so you wanna know exactly when Orochimaru bites the dust, huh? It's a classic question! Like, right up there with "Is Naruto gonna become Hokage?" (Spoiler alert: he does!). Let's dive in.
First things first, let's clarify. Orochimaru's death...it's complicated. He's kinda like that cockroach you can't ever seem to get rid of, y'know? Keeps crawling back from the brink! So, technically, he "dies" a couple of times. We gotta be specific about which instance we're talking about!
Round 1: Sasuke's Revenge
The first, and arguably the most dramatic, time Orochimaru "dies" is during his fight with Sasuke. Remember Sasuke? All moody and revenge-driven? Yeah, that guy. This all goes down in Shippuden, Episode 112, titled "The Place To Return To."
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Sasuke's been training like crazy, trying to get strong enough to take down Itachi (his brother and the source of all his teen angst). But guess what? He also kinda hates Orochimaru too for just like existing. Like, I bet even if Orochimaru didn't offer to make him stronger Sasuke would hate him anyway.
So, Sasuke basically ambushes Orochimaru, absorbing him and thinking he's, like, totally defeated him. Bye bye Orochimaru! Right? Wrong! (Dun dun DUN!)

See, Orochimaru's got this whole thing with transferring his consciousness to different bodies, like some sort of creepy ninja hermit crab. So, he's still lurking inside Sasuke. Eww!
Round 2: Itachi Cleans House (Sort Of)
Then comes Itachi. Good Ol' Itachi. He's like the clean up crew for all of the most annoying villains in Naruto. He finally has his big showdown with Sasuke, and in the process, he uses the Totsuka Blade (a mystical sword, don't ask) to seal Orochimaru away...again. This happens during Shippuden, Episode 138, called "The End."

So, Orochimaru is technically killed via extraction from Sasuke's cursed seal. But is this permanent? You know the answer. He's like the Harry Houdini of the ninja world. He'll find a way to wiggle out of anything! Are we even surprised?
Round 3: Brought Back from the Dead (By...Sasuke?)
Okay, buckle up, because this is where things get really weird. Later on, during the Fourth Great Ninja War (like, the biggest, craziest ninja battle ever), Sasuke actually brings Orochimaru back to life. Yeah, you read that right. Sasuke brings back one of the last people he wants around!

This resurrection happens in Shippuden, Episode 343, "Those Who Know Everything." Sasuke uses Anko Mitarashi (remember her?) and her cursed seal to revive Orochimaru. What the heck is going on, right?
Why does Sasuke do this? Well, he needs answers about the past and figures Orochimaru is the only one who can provide them. Risky move, Sasuke! But he actually kinda chills out after this.

So...Is Orochimaru Really Dead?
So, the final answer is, no, Orochimaru doesn't really die. Not permanently, anyway. He gets sealed, absorbed, and resurrected. It's a whole thing. By the end of the series, he's still around, even helping out (in his own twisted way). He's even got a kid in Boruto! Talk about a character arc!
He becomes almost like a slightly less creepy version of himself. Still weird, still experimenting, but maybe… less evil? Okay, maybe that's pushing it! But he's definitely not the primary antagonist anymore. He's more like a quirky, questionable neighbor. That you can’t get rid of.
So, there you have it! The complicated tale of Orochimaru's many "deaths." Now, go forth and impress your friends with your newfound Naruto knowledge! And maybe go wash your hands, because thinking about Orochimaru is kinda gross. Just saying.
